GSA Salutes First Report on Sepsis in Belgium, Leading to a National Plan

The Global Sepsis Alliance is proud to celebrate a historic achievement in the fight against sepsis in Belgium. On Friday, May 31, the first-ever comprehensive report on sepsis has been officially handed over to the Belgian Minister of Health, Frank Vandenbroucke.

This landmark event was made possible also through the dedication and efforts of GSA member Sepsibel, and the remarkable contributions of sepsis survivor Ilse Malfait. Her tireless dedication, courage, and advocacy have been instrumental in bringing the urgent issue of sepsis to the forefront of national health discussions.

The journey to this achievement began with a powerful TV report on Belgian national television VRT, which highlighted the devastating impact of sepsis. In response, Minister Vandenbroucke mandated Prof. Erika Vlieghe to produce a report for the preparation of a national action plan. Prof. Vlieghe swiftly mobilized a group of 62 experts from different disciplines, including physicians, nurses, physiotherapists, and sepsis survivors, who produced the report in just six months. We extend our heartfelt congratulations to Prof. Vlieghe for her exceptional leadership and to all the experts and survivors who contributed to this groundbreaking report.

At the World Sepsis Day event on September 12, 2023.

The GSA and the European Sepsis Alliance have been early supporters of Sepsibel since its inception. Our collaboration has been driven by a shared goal to enhance sepsis awareness, improve patient outcomes, and ultimately save lives. Sepsibel’s rapid mobilization and effective advocacy efforts, exemplified by the work of Ilse Malfait, have been truly inspiring. Her personal journey as a sepsis survivor has brought a powerful and relatable voice to the cause, helping to raise awareness and drive change at a national level. Ilse shared her story at the GSA World Sepsis Day event on September 12, 2023.

Reflecting on this historic milestone, Prof. Konrad Reinhart, Founding President of the Global Sepsis Alliance, stated: “We congratulate Sepsibel, Ilse Malfait, Prof. Vlieghe, and Minister Vandenbroucke for achieving this historic milestone in record time. The swift production of this report within just six months is a testament to the dedication and collaborative spirit of everyone involved. This achievement will undoubtedly pave the way for future advancements in sepsis awareness and management.”

Dr. Mariam Jashi, CEO of the Global Sepsis Alliance joins Prof. Reinhart in his congratulatory note to Belgium colleagues and notes: “Minister Vandenbroucke demonstrated a truly remarkable leadership, and we hope Belgium will inspire other EU policymakers to urgently prioritize sepsis in national and regional health policies in line with the 2017 World Health Assembly Sepsis Resolution. Belgium has also demonstrated best practice for people-centered and evidence-based health policy-making through active engagement of multi-disciplinary teams and sepsis survivors in the dialogue. As the GSA, we are especially proud of Ilse Malfait and our esteemed colleagues at Sepsibel for their inspiring fight that led to this critically important achievement".  

As we celebrate this significant achievement, we remain focused on the future. The Global Sepsis Alliance will continue to support Sepsibel as we work towards the implementation of a national sepsis plan in Belgium.

We extend our deepest gratitude to all who have contributed to this milestone and look forward to continuing our collaborative efforts in the fight against sepsis.

THE REPORT AT A GLANCE

The submission of this report is not just an achievement in itself, but it also marks the beginning of a crucial process. The ultimate objective is to develop a national sepsis plan for Belgium, a comprehensive strategy that will ensure better prevention, recognition, and management of sepsis across the country. This first step lays the groundwork for significant improvements in public health and patient care.

The Belgian Sepsis National Action Plan (Be-SNAP) focuses on seven key areas to combat sepsis:

Awareness and Knowledge:

  • Increase public awareness and understanding of sepsis.

  • Educate healthcare providers on early recognition and management of sepsis.

  • Develop a National Sepsis Foundation to serve as a hub for educational materials and support.

Prevention and Safeguarding Antimicrobials:

  • Strengthen healthcare access, particularly for vulnerable populations.

  • Promote vaccination and infection prevention measures.

  • Implement antimicrobial stewardship programs to prevent the misuse of antibiotics and combat antimicrobial resistance.

Early Warning Systems:

  • Develop and validate sepsis screening tools for use in various healthcare settings, including long-term care facilities, primary care, and hospitals.

  • Implement early warning scores and rapid response systems to detect and manage sepsis promptly.

Early Adequate Treatment:

  • Ensure timely administration of antibiotics and supportive care.

  • Provide large-scale education for healthcare providers on basic and advanced sepsis treatment.

  • Guarantee 24/7 availability of specialized care teams for severe cases.

Care Trajectory for Sepsis Survivors:

  • Develop a multidisciplinary rehabilitation pathway addressing physical, psychological, and neurological needs.

  • Ensure seamless transition and follow-up care from hospital to home.

  • Provide education on post-sepsis syndrome and support for survivors and their families.

Ethical Considerations and Advanced Care Planning:

  • Educate healthcare providers and the public about advance care planning and critical illness outcomes.

  • Support general practitioners and specialists in implementing advance care planning.

  • Ensure the availability of advance directives for all relevant healthcare providers.

Research and Surveillance:

  • Establish a Belgian sepsis registry to collect detailed data on sepsis cases.

  • Promote sepsis research and international collaboration.

  • Develop real-time analysis and reporting systems to monitor sepsis trends and improve patient care.

These pillars aim to reduce the incidence and impact of sepsis in Belgium through comprehensive strategies involving prevention, early detection, effective treatment, and continuous support for survivors. The plan emphasizes collaboration among healthcare providers, researchers, and patient advocacy groups to achieve these goals.

Simone Mancini
Dr. Mariam Jashi Addresses the 77th World Health Assembly to Prioritize Sepsis
No mother and child should die due to the lack of essential equipment and supplies to timely identify and timely treat Sepsis.
— Dr. Mariam Jashi, CEO of the Global Sepsis Alliance

Today, Dr. Mariam Jashi addressed the 77th World Health Assembly, urging the global health community to prioritize the fight against sepsis.


This Constituency Statement addresses agenda item 11.7 and is supported by the following 5 Non-State Actors: Humatem, International College of Surgeons (ICS), International Federation of Hospital Engineering (IFHE), International League of Dermatological Societies (ILDS), and the Medical Women’s International Association (MWIA).

The Non-State Actors supporting the statement called for the UN Member States and the Secretariat to prioritize the prevention, early detection, and effective management of sepsis.

Despite progress, sepsis affects 26.2 million women and 20.3 million children every year.

Sepsis widens inequality gaps, as women and children living in poverty are at higher risk.

Without a reinvigorated response to sepsis, health-related Sustainable Development Goals for maternal, neonatal, and child health cannot be achieved.

Yet, sepsis remains almost invisible in the global health architecture. Sepsis receives disproportionally low political attention and financial investments compared to its human and economic burden.

When we rightly prioritize Antimicrobial Resistance, we have to remember that the 5 million AMR-related deaths are part of 13 million sepsis-related deaths.

Therefore, we call on the Member States to urgently prioritize sepsis as recommended by the World Health Assembly Resolution WHA70.7

  • We specifically call for the development and implementation of national action plans and policies for sepsis. 

  • We urgently call for evidence-based sepsis clinical pathways for pediatric and adult populations, with a special focus on perinatal care services to ensure safe motherhood practices. 

  • No mother and child should die due to the lack of essential equipment and supplies to timely identify and timely treat sepsis. Diagnostic devices, live-saving antibiotics, oxygen, and treatment facilities for sepsis-related organ dysfunction should be universally accessible. 

  • Sepsis literacy should be enhanced, and we shall further strengthen vaccination and water and sanitation practices as key elements of sepsis prevention. 

  • Finally, public and private stakeholders should prioritize research and development for better quantity and quality of data, and novel solutions for prevention, early detection, and effective treatment of sepsis.

Katja Couball
Session “How Does Hypervolemia Increase the Mortality Risk in Sepsis?” from the 2024 WSC Spotlight Now Available on YouTube and as a Podcast

Session 4 from the 2024 World Sepsis Congress Spotlight is now available on YouTube (embedded above) and as a Podcast on Apple Podcasts (search for World Sepsis Congress in your favorite podcast app).


Session 4: How Does Hypervolemia Increase the Mortality Risk in Sepsis?

Desired and Undesired Effects of Fluids
Manu Malbrain, International Fluid Academy, Poland

Diagnosis and Management of Hypervolemia in Sepsis
Sheila Myatra, Asia Pacific Sepsis Alliance, India

Can Early Use of Vasopressors Avoid Hypervolemia?
Jean-Louis Teboul, University Paris-Saclay, France

The Safety Limits to Stop Fluid Infusions
Ludhmila Hajjar, University of São Paulo, Brazil

Fluid Removal: When and How?
Marlies Ostermann, Guy’s and St Thomas’ NHS Foundation Trust, United Kingdom


Sessions are released weekly on Tuesdays. The next session will be ‘The Role of Biomarkers in the Early Detection of Sepsis’ on June 4, 2024.

You can already subscribe on either platform to be automatically notified once new sessions are available.


Full Release Schedule

  • S1: Opening Session: The Renewed Global Agenda for Sepsis – Tuesday, May 7, 2024

  • S2: The Need for Early Diagnosis and Treatment of Sepsis in Surgical Patients – Tuesday, May 14, 2024

  • S3: Data, AI, and Predictive Modeling in Sepsis – Tuesday, May 21, 2024

  • S4: How Does Hypervolemia Increase the Mortality Risk in Sepsis? – Tuesday, May 28, 2024

  • S5: The Role of Biomarkers in the Early Detection of Sepsis – Tuesday, June 4, 2024

  • S6: Detecting Sepsis in the Ventilated Patient – Tuesday, June 11, 2024

  • S7: Closing the Needs in Pediatric Sepsis – Tuesday, June 18, 2024

  • S8: Personalized Approaches to Sepsis Management – Tuesday, June 25, 2024

  • S9: Challenges and Solutions for Early Recognition and Treatment of Sepsis – Tuesday, July 2, 2024


Marvin Zick
Join the Free Livestream – Multi-Stakeholder Dialogue on the 2030 Global Agenda for Sepsis

The ‘Multi-Stakeholder Dialogue on the 2030 Global Agenda for Sepsis’ in Geneva will take place today, Tuesday, May 28 – and it’s not too late to join the free livestream on YouTube (embedded above).

We will start at 12:30h Central European Summer Time (click here to see your time zone) and we are thrilled to present the draft of the 2030 Global Agenda for Sepsis and welcome interventions from high-ranking international stakeholders.

Join the livestream now and interact with us and other viewers, directly in the chat on YouTube.

In case you can’t make it live, the event will be available for recap as soon as it has concluded, at the same link and embedded above.


About the Event

The GSA is delighted to co-organize this pivotal event in cooperation with the UNITE Parliamentarians Network for Global Health (UNITE), the Virchow Foundation for Global Health, the Clinton Health Access Initiative (CHAI), the Sepsis Stiftung, Medical Women’s International Association (MWIA), and the Global Antibiotic Research and Development Partnership (GARDP).

The 2030 Global Agenda for Sepsis is the first comprehensive multi-year strategic plan, consolidating the latest evidence and knowledge on

  • the human, societal, and economic burden of sepsis

  • key foundations and achievements in the global fight against sepsis over the past two decades

  • remaining challenges toward more effective prevention, early identification, and treatment of sepsis, and

  • the way forward for reinvigorating the sepsis response at global, regional, and national levels.

Marvin Zick
Sepsis Survivors Shahrzad Kiavash and Krista Bracke Meet WHO's Dr. Tedros at Walk the Talk Event in Geneva

Amazing sepsis survivors and Global Sepsis Alliance (GSA) representatives Shahrzad Kiavash and Krista Bracke had the great honor to personally meet Dr. Tedros, Director General of the World Health Organization (WHO), at the Walk the Talk: Health for All Challenge in Geneva on Sunday, May 26. Organized by WHO for the fifth year in a row, the event brought together thousands of health advocates to the start of the 77th World Health Assembly. A unique opportunity to raise awareness of the sepsis challenge.

Shahrzad Kiavash is a Swedish triathlete and Krista Bracke a Belgian journalist. They both survived sepsis some years ago but with irreversible consequences such as a double below-knee amputation. 

Shahrzad and Krista had the opportunity to briefly stress the global burden challenge of sepsis whereas Dr. Tedros highlighted again his support to the sepsis cause. 

This recognition of sepsis by Dr. Tedros is of such importance to all sepsis survivors and their families. As not being taken seriously (even by certain health professionals) is devastating. 
— Krista Bracke
The consequences of surviving a sepsis can be truly heavy, both for the survivors and the loved ones. To be able to address the burden of sepsis to Dr. Tedros was of great importance.
— Shahrzad Kiavash

The GSA is leading the development of the first multiyear global strategy for sepsis which will be an inclusive and participatory process in which sepsis survivors and their families will have an important role to play. The Alliance is looking forward to launching this strategy, the 2030 Global Agenda for Sepsis, on September 13th at World Sepsis Day, in close partnership with the WHO, other UN-agencies and strategic partners at the GSA.

In parallel to the 77th Session of the World Health Assembly on May 28, 2024, the Global Sepsis Alliance will host a multi-stakeholder dialogue on the 2030 Global Agenda for Sepsis.

Katja Couball
Dr. Jashi Calls UN Member States to Urgently Synergize Sepsis and AMR Policies 
The face behind every AMR-related death is a face of a child, a woman or man, suffering and dying from sepsis
— Dr. Mariam Jashi, CEO of the Global Sepsis Alliance

Upon the invitation of Mr. Dennis Francis, President of the United Nations General Assembly, Dr. Mariam Jashi addressed the multi-stakeholder hearing in New York in preparation for the UN General Assembly High-Level Meeting on Antimicrobial Resistance (AMR). Dr. Jashi was invited as a panelist on adequate, predictable, and sustainable financing for AMR.

The CEO of the Global Sepsis Alliance congratulated the global health leaders for positioning antimicrobial resistance on the high-level political agenda, ensuring that over 170 counties have developed national action plans and that AMR has been prioritized in One Health Quadripartite agreement for the health of people, animals, and ecosystems.

At the same time, Dr. Jashi called the UN Member States and multiple stakeholders to ensure that in every political dialogue and decision-making process, AMR is discussed as part of broader global health challenges that require holistic solutions.

 On the necessity to urgently synergize sepsis and AMR policies and action, Dr. Jashi noted the following:

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 “The Global Sepsis Alliance is delighted that national and global health authorities and increasingly the agriculture and environmental sectors recognize that almost 5 million deaths are associated or attributed to antimicrobial resistance. However, these 4.95 million AMR-related deaths are only part of the 13.7 million sepsis-related deaths every year. The face behind every AMR-related death is the face of a child, a woman, or a man, suffering and dying from sepsis. Therefore, we need to urgently prioritize synergies between the AMR and sepsis agenda at global, regional, and national levels, and ensure that the political declaration of the High-Level Meeting on AMR adequately positions sepsis”

Furthermore, Dr. Jashi stressed that AMR should be part of a more comprehensive agenda for health-related SDGs, Universal Health Coverage, and the Pandemic Accord. “We can find better solutions for AMR only through extending UHC to at least 1 billion more people globally and building more resilient health systems” noted the GSA CEO.

Mariam Jashi concluded that a truly holistic and integrated approach to AMR, including through the One Health Quadripartite agreement, calls for maximum synergies and minimal fragmentation. Therefore, the High-Level Political Declaration for AMR should reflect the critical linkages of AMR with Universal Health Coverage, the Pandemic Accord, and the need for reinvigorated action for sepsis at global, regional, and national levels. Said political declaration should also call for adequate and sustainable funding from national governments, the stronger role of Parliamentarians in policy and budget decisions, and additional resources from official development assistance, public-private partnerships, and innovative financing solutions.

Regarding financial sustainability, Dr. Jashi discussed 5 major platforms for leveraging domestic resources for a multi-sectoral response to AMR.

  1. First, in line with the Quadripartite agreement, national governments should establish multi-sectoral coordination mechanisms with the engagement of health, environment, agriculture, and finance ministries. Joint inter-ministerial work on costing national action plans for AMR will be key for reaching a consensus on the national investment cases and securing sufficient and sustainable domestic funding.

  2. Second, Parliamentarians should be more actively engaged in the global health architecture, including AMR. Parliamentarians are direct representatives of local constituencies, they are the ultimate decision-makers to approve national laws and budgets and can hold governments accountable for execution and results. Therefore, legislative platforms, including parliamentary hearings and budget approval processes should be utilized to secure adequate accountability and funding.

  3.  Third, even if donor governments and international finance institutions contribute to the overall pool of multilateral funding and international development aid, performance-linked loans and grants can catalyze additional domestic investments for AMR. For example, the World Bank can prioritize AMR and sepsis-related key performance indicators in their budget support loans as the conditionalities for initial or subsequent tranches.

  4.  The Global PPPs, such as GAVI or the Global Fund, can not only integrate AMR and sepsis responses under the HSS portfolios but eventually catalyze additional domestic funding from national governments through phasing out and full transition from donor support.

  5.  Finally, innovative financing mechanisms, such as global or national solidarity taxes or voluntary solidarity platforms can leverage additional funding solutions. For example, the Oxygen initiative of UNITAID directly responds to the clinical management needs of AMR and sepsis both for routine UHC programs and the Pandemic Response.


The complete video recording of the meeting, including the interventions of Dr. Jashi, can be accessed at minute 35:21.

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Katja Couball
Session “Data, AI, and Predictive Modeling in Sepsis” from the 2024 WSC Spotlight Now Available on YouTube and as a Podcast

Session 3 from the 2024 World Sepsis Congress Spotlight is now available on YouTube (embedded above) and as a Podcast on Apple Podcasts (search for World Sepsis Congress in your favorite podcast app).


Session 3: Data, AI, and Predictive Modeling in Sepsis

New Data Initiatives for Monitoring Sepsis Globally
Paul Turner, Madihol Oxford Tropical Medicine Research Unit, Cambodia

Data Partnerships: Leveraging Insights from Emerging Infections to Fight Sepsis
Laura Merson, ISARIC, University of Oxford, United Kingdom

Can AI Models Really Improve Sepsis Outcomes?
Paul Elbers, Amsterdam UMC, The Netherlands

Developing Equitable AI for Sepsis Prediction in Children
María del Pilar Arias, Dr. Ricardo Gutiérrez Children’s Hospital, Argentina

From the Research Lab to the Wards: Designing AI Systems for Patient Safety and Clinical Usability
Chris Paton, University of Otago, New Zealand


Sessions are released weekly on Tuesdays. The next session will be ‘How Does Hypervolemia Increase the Mortality Risk in Sepsis?’ on May 28, 2024.

You can already subscribe on either platform to be automatically notified once new sessions are available.


Full Release Schedule

  • S1: Opening Session: The Renewed Global Agenda for Sepsis – Tuesday, May 7, 2024

  • S2: The Need for Early Diagnosis and Treatment of Sepsis in Surgical Patients – Tuesday, May 14, 2024

  • S3: Data, AI, and Predictive Modeling in Sepsis – Tuesday, May 21, 2024

  • S4: How Does Hypervolemia Increase the Mortality Risk in Sepsis? – Tuesday, May 28, 2024

  • S5: The Role of Biomarkers in the Early Detection of Sepsis – Tuesday, June 4, 2024

  • S6: Detecting Sepsis in the Ventilated Patient – Tuesday, June 11, 2024

  • S7: Closing the Needs in Pediatric Sepsis – Tuesday, June 18, 2024

  • S8: Personalized Approaches to Sepsis Management – Tuesday, June 25, 2024

  • S9: Challenges and Solutions for Early Recognition and Treatment of Sepsis – Tuesday, July 2, 2024


Marvin Zick
Multi-Stakeholder Dialogue on the 2030 Global Agenda for Sepsis – Geneva, May 28, 2024

On May 28, 2024, the Global Sepsis Alliance is hosting a multi-stakeholder dialogue on the 2030 Global Agenda for Sepsis in Geneva, Switzerland, in parallel to the 77th Session of the World Health Assembly. The GSA is delighted to co-organize this pivotal event in cooperation with the UNITE Parliamentarians Network for Global Health (UNITE), the Virchow Foundation for Global Health, the Clinton Health Access Initiative (CHAI), the Sepsis Stiftung, Medical Women’s International Association (MWIA), and the Global Antibiotic Research and Development Partnership (GARDP).

The 2030 Global Agenda for Sepsis is the first comprehensive multi-year strategic plan, consolidating the latest evidence and knowledge on

  • the human, societal, and economic burden of sepsis

  • key foundations and achievements in the global fight against sepsis over the past two decades

  • remaining challenges toward more effective prevention, early identification, and treatment of sepsis, and

  • the way forward for reinvigorating the sepsis response at global, regional, and national levels.

Please consider that in-person participation in the event is by invitation only, but we will provide a free livestream on YouTube (embedded above), starting at 12:30h CEST (Berlin/Geneva Time) on Tuesday, May 28, 2024. You can register below to receive a reminder when the livestream starts. If you would like to join the event in Geneva in person, please contact us.


Reminder – YouTube Livestream

Marvin Zick