Sessions 12 and 13 from the 5th World Sepsis Congress Now Available on YouTube and as a Podcast

Sessions 12 and 13 from the 5th World Sepsis Congress are now available on YouTube (embedded above) and as a podcast wherever you get your podcasts (search for World Sepsis Congress in your favorite podcast app, Apple Podcast link).


Session 12: Pediatric Sepsis: The LMICs Cannot Wait for Improved Outcomes Any Longer

Moderated by Fouzia Shafique from the United States

How to Use the Phoenix Sepsis Criteria in LMICs
Niranjan ‘Tex’ Kissoon, Global Sepsis Alliance, Canada

Progress in Sepsis Care in LMICs
John Appiah, World Health Organization, Ghana

Progress to Personalized Care in Resource-Poor Settings – The Omics
Teresa Kortz, University of California, San Francisco, United States

Does AI Offer Benefits in Resource-Poor Settings?
María del Pilar Arias, Latin American Society of Pediatric Intensive Care, Argentina

The Fluid Story – From Liberal to Frugal
Suchitra Ranjit, Apollo Children’s Hospital, India


Session 13: State of the Art in Sepsis Research: Emerging Immunomodulatory Approaches

Moderated by Imrana Malik from the United States

Immunomodulatory Therapies – Where Are We Currently?
Evangelos Giamarellos-Bourboulis, European Sepsis Alliance, Greece

TREM-1 Inhibition
Bruno François, University Hospital of Limoges, France

IL-6 Inhibition
Nuala Meyer, Hospital of the University of Pennsylvania, United States

Immunomodulatory Therapies in Pediatric Patients
Mark Hall, The Ohio State University College of Medicine, United States

Adrenomedullin – Treating the Vascular Endothelium
Stephan Witte, Adrenomed, Germany

C5a Inhibition
Michael Bauer, Jena University Hospital, Germany


Two new sessions are released weekly on Tuesdays. The next and final sessions will be ‘S14: Sepsis in Emergencies and Humanitarian Crisis’ and ‘S15: Prevention and Rehabilitation of Long-Term Sequelae From Sepsis’ on June 3, 2025.

You can already subscribe on either platform to be automatically notified once new sessions are available.


Full Release Schedule

S1: Opening Session – Tuesday, April 15, 2025

S2: Sepsis Epidemiology and Clinical Data – Tuesday, April 22, 2025

S3: The Voices of Patients in Advocacy, Research, and Beyond – Tuesday, April 22, 2025

S4: Novel Approaches to Pathogen Detection and Sepsis Diagnostics – Tuesday, April 29, 2025

S5: The Immunization Agenda for Sepsis – Tuesday, April 29, 2025

S6: Pathways for Sepsis Care – Integrated Emergency, Critical, and Operative Care (ECO) – Tuesday, May 6, 2025

S7: Bridging Sepsis Knowledge Gaps in HICs and LMICs – Tuesday, May 6, 2025

S8: Infection Prevention and Control in Community and Healthcare Settings – Tuesday, May 13, 2025

S9: Reducing Sepsis Mortality Through System Change – Lessons from Trailblazing Countries – Tuesday, May 13, 2025

S10: AI Solutions for Sepsis – Tuesday, May 20, 2025

S11: The Research Agenda for AMR and Sepsis – Tuesday, May 20, 2025

S12: Pediatric Sepsis: The LMICs Cannot Wait for Improved Outcomes Any Longer – Tuesday, May 27, 2025

S13: State of the Art in Sepsis Research: Emerging Immunomodulatory Approaches – Tuesday, May 27, 2025

S14: Sepsis in Emergencies and Humanitarian Crisis – Tuesday, June 3, 2025

S15: Prevention and Rehabilitation of Long-Term Sequelae From Sepsis – Tuesday, June 3, 2025


Marvin Zick
Dr. Mariam Jashi Calls on World Health Assembly to Prioritize Sepsis

At the 78th World Health Assembly (WHA), Dr. Mariam Jashi delivered two official statements, calling on WHO Member States and key global health players to prioritize Sepsis as the leading cause of death and disability worldwide.  

Dr. Jashi attended WHA78 in her capacity as Secretary General of the Medical Women’s International Association (MWIA) and CEO of the Global Sepsis Alliance (GSA). She advocates for Sepsis under the strategic partnership agreement between GSA and MWIA, announced on March 8, 2024. 

Amidst the diminishing multilateralism and the de-prioritization of global health, Dr. Jashi urged the government to ensure increased national investments in Universal Health Coverage (UHC), and integration of Sepsis into UHC, as the best proxy indicator of how well national health services function. She reiterated that the global community will not be able to attain Sustainable Development Goals and UHC without prioritizing Sepsis. 

“We cannot attain Sustainable Development Goals and Universal Health Coverage without prioritizing Sepsis.”
— Dr. Mariam Jashi, CEO, Global Sepsis Alliance 

Dr. Jashi also participated in high-level discussions on strengthening the global health architecture for health emergency prevention, preparedness, and response.

She expressed concern that the current global architecture underestimates the fact that, similar to COVID-19, every future disease outbreak or pandemic will face escalated risks of Sepsis, as the final common pathway to death and disability. She further warned that armed conflicts, the climate crisis, and large-scale displacement increase the risk of infection and Sepsis among civilians, healthcare workers, humanitarian personnel, and peacekeeping forces. 

Therefore, she urged that the global architecture for health emergencies should prioritize stronger risk communication, surveillance, and capacity building for Sepsis, along with increased R&D for new vaccines, antimicrobial therapies, and pathogen-agnostic immunomodulatory solutions. 

“Similar to COVID-19, every future disease outbreak or pandemic will face escalated risks of Sepsis, as the final common pathway to death and disability.”
— Dr. Mariam Jashi, CEO, Global Sepsis Alliance 

The 78th World Health Assembly was historic for the Global Sepsis Alliance, marking the first official WHA78 Side Event on Sepsis, held on May 24. A detailed report on the Sepsis WHA78 Side Event will be posted separately in due course.

Katja Couball
May 24 – Official Side Event on Sepsis at the 78th World Health Assembly

The Global Sepsis Alliance (GSA) through its strategic partnership with the Medical Women’s International Association and collaboration with the Governments of Guyana and Egypt, the UNITE Parliamentarians Network for Global Health, the Virchow Foundation, Sepsis Stiftung, and CHAI, is proud to convene the first Official Side Event on Sepsis at the 78th World Health Assembly (WHA) in Geneva.

On behalf of all co-organizing partners, the GSA cordially invites Member State delegations, specialized agencies, and non-state actors attending the ongoing 78th WHA to join us on May 24 from 12:30 to 13:50 at Palais des Nations, Room XXII.

This Side Event will feature opening remarks and interventions from distinguished leaders in global health, including high-level officials from co-convening partners and the World Health Organization.

In line with the 2030 Sustainable Development Goals (SDGs) and the WHO’s Fourteenth General Programme of Work, the meeting aims to catalyze transformative actions for saving 2 million lives from Sepsis by 2030 through stronger political leadership, health systems strengthening, R&D, and more effective prevention and management of Sepsis during health emergencies.

The Side Event aims to consolidate political momentum for the 2030 Global Agenda for Sepsis launched by the Global Sepsis Alliance at the German Parliament in September 2024 in partnership with the Global Health Sub-Committee of the German Bundestag.

The Global Sepsis Alliance and its partners were honored to receive a special video address from Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, for the occasion of the Agenda launch.

The 2030 Global Agenda for Sepsis is the first global strategy on how to reduce the suffering of 48.9 million children, women, and men annually and improve health outcomes from Sepsis. It was elaborated through the engagement of more than 70 stakeholders and Sepsis survivors from 6 geographic regions.

Engaging the governments of Guyana and Egypt, the Side Event will also encourage other UN Member States to join the High-Level Political Panel on Sepsis to be established in September 2025. The Panel will bring together Heads of State, Health Ministers, and Parliamentarians for positioning Sepsis higher in the global political agenda, including at G7/G20, UN, WHA, national and regional Parliaments, Ministerial summits, and other forums.

Please join us at the upcoming Official WHA78 Side Event on Sepsis and our common vision for making the fight against Sepsis the Next Success Story in Global Health.

Katja Couball
Trofeo Elia Epifanio – Racing to Save Lives

May 10 was a beautiful and moving day in Wohlen, Switzerland. The kart track came alive with the energy of 50 children and hundreds of attendees during the Trofeo Elia Epifanio – a charitable racing event held in memory of Elia Epifanio, a promising young Swiss karting talent who tragically passed away from sepsis two years ago.

This was the second race organized by Elia’s parents, Jennifer and Daniele Epifanio, who have turned their grief into hope, remembrance, and an inspiring advocacy effort. The event raised CHF 11,600 to support the Swiss Sepsis Program at the Children’s Hospital Zurich (KISPI).

Friends and family from across Switzerland and Italy, and renowned race car drivers and journalists, came together to support the Epifanio family and their cause.

Dr. Mariam Jashi, CEO of the Global Sepsis Alliance (GSA), attended the event alongside her esteemed colleague, Dr. Nora Lüthi, Medical Program Manager of the Swiss Sepsis Program, which was initiated under the leadership of Prof. Luregn Schlapbach, Professor of Pediatric Intensive Care at the University of Zurich and an internationally recognized scholar in pediatric sepsis.

On behalf of the Global Sepsis Alliance, Dr. Jashi extended her deepest gratitude and admiration to the Epifanio family for turning their immense loss into an example of humanity and compassion. Through Elia’s Trophy, Daniele and Jennifer are now fighting to protect thousands of other children from sepsis.

While addressing the audience, GSA’s CEO highlighted the shocking burden of sepsis and the urgency of action. Sepsis affects nearly 50 million people, yet we do not hear about it in the media or political debates. We must change this reality, and each of us has a role to play. We must raise awareness and ensure that every member of society understands the threat of sepsis, knows how to recognize it early, and knows how to act. We must ensure that when a child or adult arrives at a primary healthcare facility or hospital, every general practitioner, pediatrician, infectious disease specialist, emergency medical team member, or intensivist is fully equipped to provide timely and life-saving care.

Dr. Jashi, as a former Member of Parliament and Deputy Health Minister of Georgia, pledged to mobilize Swiss and global political leaders and World Health Organization (WHO) officials for future Trofeo events, as Elia’s story should be known to policymakers and decision-makers.

May 10 in Wohlen was indeed a beautiful and unforgettable day. But this day should not have happened. What happened to Elia and his family should not be allowed to happen again, not in Switzerland, not in any other country.

Looking at Elia’s photos and hearing his story leaves no one untouched. How can we continue to lose bright and brilliant lives like Elia’s because we failed to educate our societies – and even many healthcare professionals – on how to recognize and treat one of the leading causes of death worldwide? 

Trofeo Elia Epifanio is a celebration of Elia’s life and his love for motorsport and a true drive to save lives. In transforming their unimaginable loss into action, Jennifer and Daniele Epifanio are protecting thousands of other families from experiencing the same pain.

The Global Sepsis Alliance extends our sincerest admiration to the Epifanio family and stands ready to help ensure that the impact of Trofeo Elia Epifanio reaches even greater heights.

Marvin Zick
Sessions 10 and 11 from the 5th World Sepsis Congress Now Available on YouTube and as a Podcast

Sessions 10 and 11 from the 5th World Sepsis Congress are now available on YouTube (embedded above) and as a podcast wherever you get your podcasts (search for World Sepsis Congress in your favorite podcast app, Apple Podcast link).


Session 10: AI Solutions for Sepsis

Moderated by Katherine Urbáez from Switzerland

The Sepsis ImmunoScore – The First FDA-Approved AI Tool for Sepsis Prediction
Nathan Shapiro, Prenosis, United States

Using AI for Early Detection and Predictive Modeling of Sepsis
Sujoy Kar, Apollo Hospitals, India

AI in Antimicrobial Stewardship
Ian Hosein, University of the West Indies, St. Augustine, Trinidad


Session 11: The Research Agenda for AMR and Sepsis

Moderated by Louise Norton-Smith from the United Kingdom

WHO’s Global Research Priorities for AMR and Sepsis
Benedikt Huttner, World Health Organization, Switzerland

Early Recognition of Sepsis Needs to Become an Integral Part of Antimicrobial Stewardship Programs
Kristoffer Strålin, Karolinska Institutet, Sweden

Priorities for AMR in Hospital-Acquired Infections
Mo Yin, National University Singapore, Singapore

NeoSep1: PRACTical Considerations
Louise Hill, St. George’s, University of London, United Kingdom

AMR Research in Africa and Improving Sepsis
Elvis Temfack, Africa CDC, Ethiopia

Advancing Therapy in Critical Care: The Role of DPP3 in Mixed Shock
Karine Bourgeois, 4TEEN4 Pharmaceuticals, Germany


Two new sessions are released weekly on Tuesdays. The next sessions will be ‘S12: Pediatric Sepsis: The LMICs Cannot Wait for Improved Outcomes Any Longer’ and ‘S13: State of the Art in Sepsis Research: Emerging Immunomodulatory Approaches’ on May 27, 2025.

You can already subscribe on either platform to be automatically notified once new sessions are available.


Full Release Schedule

S1: Opening Session – Tuesday, April 15, 2025

S2: Sepsis Epidemiology and Clinical Data – Tuesday, April 22, 2025

S3: The Voices of Patients in Advocacy, Research, and Beyond – Tuesday, April 22, 2025

S4: Novel Approaches to Pathogen Detection and Sepsis Diagnostics – Tuesday, April 29, 2025

S5: The Immunization Agenda for Sepsis – Tuesday, April 29, 2025

S6: Pathways for Sepsis Care – Integrated Emergency, Critical, and Operative Care (ECO) – Tuesday, May 6, 2025

S7: Bridging Sepsis Knowledge Gaps in HICs and LMICs – Tuesday, May 6, 2025

S8: Infection Prevention and Control in Community and Healthcare Settings – Tuesday, May 13, 2025

S9: Reducing Sepsis Mortality Through System Change – Lessons from Trailblazing Countries – Tuesday, May 13, 2025

S10: AI Solutions for Sepsis – Tuesday, May 20, 2025

S11: The Research Agenda for AMR and Sepsis – Tuesday, May 20, 2025

S12: Pediatric Sepsis: The LMICs Cannot Wait for Improved Outcomes Any Longer – Tuesday, May 27, 2025

S13: State of the Art in Sepsis Research: Emerging Immunomodulatory Approaches – Tuesday, May 27, 2025

S14: Sepsis in Emergencies and Humanitarian Crisis – Tuesday, June 3, 2025

S15: Prevention and Rehabilitation of Long-Term Sequelae From Sepsis – Tuesday, June 3, 2025


Marvin Zick
Dr. Jashi Calls for Prioritizing Sepsis in Reproductive Health Research

Geneva, April 29–30 – Dr. Mariam Jashi, CEO of the Global Sepsis Alliance, participated in the 38th Meeting of the Policy and Coordination Committee (PCC) of the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), held at WHO Headquarters in Geneva.

Dr. Bruce Aylward, Assistant Director-General of the World Health Organization (WHO), and Sir Jeremy Farrar, WHO Chief Scientist, delivered special remarks to the Committee. PCC adopted the report from its 37th session and approved recommendations for the future work of the Committee. The meeting recommended that HRP continues to work on sexual and reproductive health and rights, especially in connection with climate change and pandemic prevention, preparedness, and response, through close collaboration among all co-sponsors. The Committee also discussed how science and evidence generated by HRP can best continue to effectively inform policy and counteract anti-rights movements, disinformation, and misinformation.

On April 29, Dr. Jashi addressed member states, co-sponsors, and civil society partners on behalf of the Global Sepsis Alliance, which was invited as an Observer to the PCC. She underscored the urgent need to prioritize sepsis within the human reproductive health agenda. Sepsis affects 26 million women annually, including 5.7 million pregnant women, and impacts more than 20 million children under five, among them 1.3 million newborns. Given this staggering burden, she urged the Committee to integrate sepsis as a core priority in all policy deliberations and recommendations.

Dr. Jashi also spotlighted the 2030 Global Agenda for Sepsis, calling on UN Member States to ensure the prioritization of sepsis—the cause of 1 in every 5 deaths worldwide—in all political and health policy discussions and decision-making processes.

The Global Sepsis Alliance and its leadership will continue to use every advocacy platform to elevate the position of sepsis within the global health dialogue and architecture.

 

Katja Couball
Sessions 8 and 9 from the 5th World Sepsis Congress Now Available on YouTube and as a Podcast

Sessions 8 and 9 from the 5th World Sepsis Congress are now available on YouTube (embedded above) and as a podcast wherever you get your podcasts (search for World Sepsis Congress in your favorite podcast app, Apple Podcast link).


Session 8: Infection Prevention and Control in Community and Healthcare Settings

Moderated by Maha Aljuaid from Saudi Arabia

The Sepsis Challenge Vis-à-Vis the Global Health Agenda
Jeremy Farrar, World Health Organization, Switzerland

A Global Action Plan and Monitoring Framework to Prevent Sepsis Acquired in Health Care Settings
Benedetta Allegranzi, WHO Regional Office for the Eastern Mediterranean, Egypt

Rapid Diagnostics and Diagnostic Stewardship for Preventing Infection Evolution to Sepsis
Claudia Spies, Charité – Universitätsmedizin Berlin, Germany

Preventing Sepsis Using Vaccines That Reduce Antimicrobial Resistance
Mateusz Hasso-Agopsowicz, World Health Organization, Switzerland

WASH as an IPC Measure for Sepsis Prevention
Lindsay Denny Naughton, UNICEF, United States


Session 9: Reducing Sepsis Mortality Through System Change – Lessons from Trailblazing Countries | Panel

Moderated by Simon Finfer from Australia

Decreasing Sepsis Mortality and Making Gains Despite Socio-Economic Disparities
Daniela Carla de Souza, Latin American Sepsis Institute (LASI), Brazil

How Awareness Programs Are Making a Difference in the UK
Ron Daniels, UK Sepsis Trust, United Kingdom

Phase 2 of the Australian National Sepsis Program
Carolyn Hullick, Australian Commission on Safety and Quality in Healthcare, Australia

The Swiss Sepsis National Action Plan – 2 Years Later
Nora Lüthi, University Children’s Hospital Zürich, Switzerland

Integrating Sepsis Into the Health System to Reduce Mortality from Sepsis
Sue Markey, National Clinical Program for Sepsis, Ireland

Thailand: A Fresh Perspective
Direk Limmathurotsakul, Mahidol-Oxford Tropical Medicine Research Unit, Thailand

Discussion by the Panelists


Two new sessions are released weekly on Tuesdays. The next sessions will be ‘S10: AI Solutions for Sepsis’ and ‘S11: The Research Agenda for AMR and Sepsis’ on May 20, 2025.

You can already subscribe on either platform to be automatically notified once new sessions are available.


Full Release Schedule

S1: Opening Session – Tuesday, April 15, 2025

S2: Sepsis Epidemiology and Clinical Data – Tuesday, April 22, 2025

S3: The Voices of Patients in Advocacy, Research, and Beyond – Tuesday, April 22, 2025

S4: Novel Approaches to Pathogen Detection and Sepsis Diagnostics – Tuesday, April 29, 2025

S5: The Immunization Agenda for Sepsis – Tuesday, April 29, 2025

S6: Pathways for Sepsis Care – Integrated Emergency, Critical, and Operative Care (ECO) – Tuesday, May 6, 2025

S7: Bridging Sepsis Knowledge Gaps in HICs and LMICs – Tuesday, May 6, 2025

S8: Infection Prevention and Control in Community and Healthcare Settings – Tuesday, May 13, 2025

S9: Reducing Sepsis Mortality Through System Change – Lessons from Trailblazing Countries – Tuesday, May 13, 2025

S10: AI Solutions for Sepsis – Tuesday, May 20, 2025

S11: The Research Agenda for AMR and Sepsis – Tuesday, May 20, 2025

S12: Pediatric Sepsis: The LMICs Cannot Wait for Improved Outcomes Any Longer – Tuesday, May 27, 2025

S13: State of the Art in Sepsis Research: Emerging Immunomodulatory Approaches – Tuesday, May 27, 2025

S14: Sepsis in Emergencies and Humanitarian Crisis – Tuesday, June 3, 2025

S15: Prevention and Rehabilitation of Long-Term Sequelae From Sepsis – Tuesday, June 3, 2025


Marvin Zick
Global Voices Unite: Launch of the Global Sepsis Survivor and Family Committee (GSSFC)

The Global Sepsis Survivor and Family Committee (GSSFC) has officially launched and held its first two meetings in April 2025. The GSSFC aims at bringing together sepsis survivors, family members, and advocates from across the globe with a shared goal: to elevate the voices of those affected by sepsis and help drive meaningful change worldwide.

During these early meetings, the committee laid the foundation for its work, agreeing on a core mission to share knowledge, promote survivor-led advocacy, and influence global policy. Members shared their personal experiences and discussed ways to ensure that the committee and the broader sepsis community's voices are actively involved in shaping decisions. Priorities identified include reviewing existing sepsis education and support materials, building accessible resources for survivors and families, and contributing to the global World Sepsis Day movement.

The committee also agreed on a working logo and guiding principles and began shaping how it will act as a vital link between the global sepsis community and the broader work of the Global Sepsis Alliance.

Join the GSSFC

Are you a sepsis survivor or family member passionate about making a difference? The GSSFC welcomes new members from around the world to bring diverse perspectives and help shape a future where survivors’ needs are heard, respected, and met.

To join the GSSFC, contact Simone Mancini, GSA Partnership Lead, at Simone.Mancini@global-sepsis-alliance.org

Simone Mancini