Vanessa’s Sepsis Story: From a Suspected Stomach Bug to Septic Shock

Friday, February 16, started just like any other day. I did my early morning workout, got the kids off to school, and went to work. That evening, we had a family dinner, and everything seemed normal. But as night fell, I started to feel achy and unwell. With winter break approaching, I thought, Great timing – getting sick right before a break.

That night, the chills hit me violently. By Saturday morning, I woke up with severe stomach pain and nausea. I chalked it up to a stomach bug and hoped it would pass in 24 hours. I stayed in bed most of the day, barely keeping anything down. Reluctantly, I canceled plans to see a Broadway play, thinking sleep would cure me. I didn’t even check for a fever; I didn’t think it was that serious.

By Sunday, I was still sick, and my mother insisted I go to urgent care. My husband drove me there, though walking had become difficult. I assumed I was just weak from being unwell and hungry.

At urgent care, my blood pressure was 65/44, and I was running a fever. They gave me Tylenol and were preparing to call an ambulance, but I still didn’t grasp the severity. I asked my husband to take me to the hospital instead. Every bump in the car sent waves of pain through my body.

In the ER, they immediately wheeled me past the waiting room. I thought it was luck. But after initial assessments, I noticed the nurses and doctors wearing ICU badges. CT scans were done, and I couldn’t pass urine, so a catheter was inserted. The doctors began prepping me as a suspected sepsis case. I couldn’t understand it; I was healthy. I just had a stomach bug.

As medications were started to stabilize my blood pressure, my pain increased. I was told surgery was imminent, though the source of infection was unknown. A central line was inserted into my neck to monitor and administer treatment. The surgeon spoke kindly but firmly, explaining that the scans were inconclusive and they needed to explore my abdomen.

I went into the OR, went under anesthesia, and had an arterial line inserted to monitor my blood pressure. That night, I underwent a laparotomy, and 700 ml of infected fluid was removed. They couldn’t determine the root cause, but fortunately, my organs were unharmed.

I woke up the next day intubated, my mind cloudy but aware of where I was. My husband was there saying everything was great, but I could imagine what he was seeing. I was extubated the following day. The week in the CCU was intense: I was on numerous IV antibiotics, in pain, with a giant incision and a drain. Walking was a slow shuffle, cords trailing behind me, yet I pushed myself. My brain was foggy, but I had to get home to my three children, who had no idea how sick I was. The view of a playground from my window broke my heart; I wanted to be there with them.

The nurses and doctors were incredible. They held me steady as I learned to walk again, checked my vitals, listened to my belly, and encouraged me to talk about my kids to distract from the pain. Their support helped me stay focused on recovery. When I was finally discharged, I was ecstatic to go home.

Home life was different. The first floor of my house became my world: a recliner, a commode, and the humming of life around me. The first night brought a fever spike and intense pain. I even began writing down notes for my family, fearful of returning to the hospital and not coming home. The following day, I stabilized, but recovery was slow. My once-sharp mind struggled with focus and multitasking. My strong, active body could barely walk. Emotionally, I swung from anger to sorrow.

Despite everything, I channeled my energy into recovery. I can now laugh about the stomach bug that almost killed me. I share my story widely and have encouraged at least three close friends to seek care when in pain; each had appendicitis successfully treated with simple surgery. I also rediscovered a love of exercise, which I truly believe helped save me.

Today, when I look at my giant scar and feel the creeping question of “Why me?”, I try to find perspective. I survived. My doctors recognized the signs of sepsis, and now so do I.


The article above was written by Vanessa Sparacio and is shared here with her explicit consent. The views in the article do not necessarily represent those of the Global Sepsis Alliance. They are not intended or implied to be a substitute for professional medical advice. The whole team here at the Global Sepsis Alliance and World Sepsis Day wishes to thank Vanessa for sharing her story and for fighting to raise awareness for sepsis.

Marvin Zick
GSA Formalizes Strategic Partnership with the Infectious Disease Alliance

GSA CEO, Dr. Mariam jashi, and IDA Executive Director, Rodrigo Scotini

The Global Sepsis Alliance (GSA) is proud to announce a new Memorandum of Understanding with the Infectious Disease Alliance (IDA), formalizing a partnership built on a shared conviction: sepsis cannot be tackled in isolation from the broader fight against infectious diseases.

Under the agreement, GSA and IDA become full members of one another's networks, opening the door to joint committees, working groups, and campaigns. GSA also joins IDA's Primary Healthcare Coalition and Global Health Finance Coalition, reflecting the understanding that integrated care and sustainable financing must go hand in hand. Together, the two alliances will align policy priorities, coordinate advocacy, co-host events from the World Health Assembly to the World Health Summit, and develop joint fundraising and communications initiatives.

At its heart, this partnership is about recognizing sepsis as a marker of quality of care and a central thread running through infectious disease response, AMR, and pandemic preparedness. By working as one, GSA and IDA aim to ensure sepsis advocacy is fully embedded within the wider infection management agenda, rather than treated as a parallel conversation.

We are deeply grateful to IDA Executive Director Rodrigo Scotini for his leadership and vision. This MoU marks the beginning of a shared journey. The recent appointment of Simone Mancini, GSA Partnership Lead and Director of the European Sepsis Alliance, as a member of the IDA Board of Directors, confirms the common will of the two organizations to work together towards a shared vision.

Simone Mancini
UK Department of Health Announces Historic Modern Service Framework for Sepsis

On Tuesday July 14, NHS England (NHSE) and the Department of Health and Social Care (DHSC) published the Modern Service Framework (MSF) for Sepsis, outlining a ten-year vision to transform sepsis care by 2035.

The MSF aims to reduce deaths, life-changing complications, and the long-term impact of sepsis for everyone by at least 25% over the next decade. This will be achieved through better prevention, earlier diagnosis, improved treatment, rehabilitation, research, and innovation.

The ambition is simple but powerful: to make sure every person with sepsis receives the best possible care the NHS can offer, whenever and wherever they need it.

 Dr Ron Daniels BEM, Founder and Chief Medical Officer of the UK Sepsis Trust, and Vice President of the GSA said: “The publication of the Sepsis MSF marks a significant moment for patient safety. For too long, progress in sepsis care has been held back by fragmented and inconsistent practice. This framework sets out to change that, and we welcome plans for improved diagnostics, treatment and care.“

Why a Sepsis MSF?

Modern Service Frameworks are a key part of the NHS 10-Year Health Plan. They are long-term frameworks designed to tackle the biggest health killers by setting consistent national standards and supporting high-quality, high-value, and equitable care across key clinical pathways. Sepsis is a priority condition for the new MSF because of the significant mortality, morbidity, and healthcare activity that results from it: it’s the second biggest killer after cardiovascular disease in England.

In the UK, five people lose their lives to sepsis every hour. It’s a life-threatening condition which arises when the body’s response to infection harms its own tissues and organs and is estimated to affect 245,000 people in the UK every year, claiming 48,000 lives.  82% of sepsis survivors are experiencing ‘Post-Sepsis Syndrome’ more than a year after hospital discharge, and 18% left permanently unable to work.

The MSF’s publication comes as sepsis continues to place considerable pressure on both the NHS and the wider economy. In 2024/25, sepsis was responsible for more than 154,000 emergency hospital admissions in England (based only on coded data, so almost certainly an underestimate), while new research from the York Health Economics Consortium (YHEC), commissioned by the UK Sepsis Trust, estimates that the condition costs the UK economy £23 billion annually.

What it means for patients

Sepsis is one of the biggest killers in England and tackling sepsis is a priority for the NHS. The new NHS Sepsis Modern Service Framework has a clear goal, to reduce deaths, serious illness, and long-term harm from sepsis by at least 25% by 2035. This means better, more consistent care for everyone across the country.

It will improve the way sepsis is treated right now, while also accelerating innovation and research to develop new and better treatments for the future. Looking ahead, a sustainable national research and innovation infrastructure — guided by patient experience and aligned with clear implementation pathways — will continue to drive improvements in care for generations to come.

What it means for HCPs

The Sepsis MSF addresses both the immediate need to strengthen existing care pathways and the longer-term ambition to accelerate research and innovation, developing new models of care that will transform how sepsis is prevented, identified, and treated.

Some patient groups face significantly worse outcomes from sepsis due to health inequalities. The Sepsis MSF explicitly prioritises reducing these disparities, ensuring improvements in care and outcomes are equitable and felt across all population groups and life stages.

Dr Daniels commented: “However, it’s important to remember that this is a 10-year plan and we are not expecting immediate delivery of all of its proposals. Nonetheless, it is hugely encouraging to see the framework’s suggestion that by 2035, we will have the best and most resilient infrastructure for recognising and managing sepsis, for all people and in all settings, in the world. 

"We look forward to working alongside NHSE and DHSC to ensure that this MSF fulfils its world-leading potential in transforming sepsis outcomes across our health system."

Simone Mancini
6th WSC Final Report: Statistics and Numbers from the 6th World Sepsis Congress

The 6th World Sepsis Congress has officially concluded, and we are delighted to share the final report, highlighting the remarkable reach, engagement, and impact of this year’s event.

Held on April 22 and 23, 2026, under the theme “Universal Sepsis Care for Newborns, Children, and Women,” the congress brought together healthcare professionals, researchers, policymakers, survivors, and advocates from around the world to advance knowledge and improve outcomes for some of the populations most vulnerable to sepsis.

As always, the congress was completely free to attend and featured live presentations, interactive Q&A sessions, and on-demand access to all sessions following the event.

Among this year’s highlights:

  • 7,824 registrations from more than 150 countries, despite registration being entirely optional

  • For the first time ever, World Sepsis Congress was streamed directly to YouTube, making the congress even more accessible across the web, mobile devices, and smart TVs

  • 92 speakers, panelists, and moderators from 35 countries, representing every region of the world

  • More than 19 hours of educational sessions, including 15 scientific sessions and two live panel discussions

  • An average of 1,345 views per session and 175 simultaneous live viewers, making this the most-watched World Sepsis Congress to date

  • Support and endorsement from more than 40 international organizations.

Participant feedback was once again overwhelmingly positive. Attendees rated the congress 9.29 out of 10 overall, with similarly high ratings for both the quality of the speakers (9.2/10) and the relevance of the scientific content (9.18/10). Speakers and moderators also reported an excellent experience, giving the congress an overall rating of 9.26 out of 10.

The congress also reflected our continued commitment to diversity and global representation. More than 60% of speakers were women, and faculty members came from 35 countries across Europe, North America, Africa, Asia-Pacific, the Middle East, and Latin America.

World Sepsis Congress continues to demonstrate that high-quality global medical education can be accessible to everyone, regardless of geography or financial resources.

The complete report includes detailed statistics on registrations, audience demographics, viewing figures, participant and speaker satisfaction, and much more.

Download the full report to explore the complete results and insights from the 6th World Sepsis Congress.

Last but not least, we thank our Scientific Committee, speakers, moderators, supporting organizations, sponsors, and, above all, the thousands of participants who joined us from around the world.

We look forward to welcoming you to the 7th World Sepsis Congress, taking place on April 21 and 22, 2027, under the theme “Reimagining Sepsis Care: Innovation, Implementation, and Global Equity.”

Marvin Zick
Shaping Fluid Stewardship: IFAD 2026 in Antwerp, December 3-5, 2026

A reimagined 3‑day, course-based meeting on fluid stewardship, hemodynamic monitoring, and physiology-driven critical care, IFAD 2026 marks the 15th anniversary of the International Fluid Academy Days with an intentionally small, highly interactive program designed to translate physiology into real bedside decisions for multidisciplinary clinicians.


Introduction – Why Antwerp in December 2026?

From 3–5 December 2026, Ziekenhuis Aan de Stroom (ZAS) Cadix, Antwerp, Belgium, will host the 15th anniversary edition of the International Fluid Academy Days (IFAD 2026).

This landmark meeting brings together clinicians who care for acutely ill and perioperative patients to focus on one central theme: doing fluid therapy better, through structured, interactive learning.

Unlike a traditional large congress, IFAD 2026 has been reimagined as a course-based experience where every session is designed to connect physiology, monitoring, and clinical reality. Antwerp provides the backdrop for a three-day journey that is deliberately paced, integrated, and geared toward practical change in daily practice.


A different kind of critical care meeting

IFAD 2026 is explicitly designed as a course-based, interactive meeting focused on clinical practice, not as a passive, auditorium-driven congress. The organizers have built the program around the premise that learning is most effective when it is active, structured, and clinically relevant.

Instead of long lectures delivered to hundreds of silent listeners, the meeting emphasizes small-group teaching, case-based discussions, interactive sessions, and direct exchange with international experts. Participants are not just attendees; they become active contributors in a shared learning environment where questions, doubts, and local practices are openly discussed. This format creates space to explore complex fluid decisions and hemodynamic dilemmas in depth, with faculty guidance.


A structured three-day learning journey

The IFAD 2026 program is intentionally constructed as a progressive three-day pathway, where each day builds on the previous one. The aim is to move from fundamentals to advanced application in a logical, clinically meaningful sequence.

Day 1 – Foundations of fluid therapY

The first day concentrates on the core principles of fluid management. Participants revisit key aspects of fluid physiology and fluid types, and work through the fundamentals of maintenance, replacement, and resuscitation strategies.

Interactive and case-based sessions are used in the afternoon to reinforce these concepts and connect them directly to typical clinical scenarios, such as early shock resuscitation or perioperative fluid prescriptions. By the end of the day, participants should have a clearer, physiology-driven framework for deciding when and how to start fluids, and how to avoid inappropriate or excessive administration.

Day 2 – Applying principles to real patients

On Day 2, the focus shifts to applying fluid therapy principles in perioperative and critical care settings. Sessions explore electrolyte disturbances, organ-specific challenges, and complex clinical contexts where fluids interact with vasopressors, ventilation, and organ support.

Extended case-based discussions allow participants to walk step by step through real-world situations, from the emergency department to the operating room and ICU. Questions such as “How do I adapt my fluid strategy in a patient with coexisting kidney injury and respiratory failure?” or “What does this hemodynamic monitoring profile mean for my next fluid decision?” can be explored with faculty and peers.

Day 3 – Advanced concepts and integration

The final day brings the learning journey to an advanced level, focusing on fluid-related pathophysiology, organ interactions, metabolic disturbances, and AI. Participants examine how cumulative fluid balance, capillary leak, venous congestion, and organ cross-talk influence outcomes in critically ill and high-risk surgical patients.

IFAD 2026 concludes with an interactive quiz and diploma-style session, designed to consolidate learning, highlight key take-home messages, and ensure that participants leave with a coherent, integrated view of fluid stewardship. The three days are offered as a continuous course; participation is structured as a full 3-day experience rather than single-day drop-in attendance, protecting continuity and progression.


Educational philosophy: active, structured, clinically grounded

The educational philosophy behind IFAD 2026 is clear: learning should be active, structured, and directly linked to bedside decisions. The meeting uses small groups, interactive formats, and real cases to keep participants engaged and to mirror the complexity of real clinical practice.

Participation is intentionally limited to preserve interaction and ensure that every clinician has the opportunity to ask questions, debate options, and receive feedback from faculty. Rather than expanding in size, this 15th edition focuses on refining how we learn – prioritizing depth over breadth, and dialogue over one-way communication. Over the past 15 years, the International Fluid Academy has contributed to education and research in fluid management; IFAD 2026 represents the next chapter in that journey by focusing on the quality of the learning environment.


What you will take back to the bedside

IFAD 2026 is designed so that participants not only acquire new knowledge but also develop practical strategies for implementation in their own units. Throughout the three days, the emphasis remains on translating physiology and hemodynamic monitoring into concrete, patient-centered decisions.

Clinicians can expect to leave with:

  • A clearer, stepwise approach to fluid assessment and prescription, from maintenance to resuscitation

  • An improved understanding of how to integrate hemodynamic monitoring into decision-making, rather than using it in isolation

  • Practical insights into preventing and managing fluid overload, congestion, and organ dysfunction

  • Frameworks to support fluid stewardship programs and more rational, team-based fluid management in daily practice

By working through cases in an interactive setting, participants can stress-test these concepts against their own experience and local protocols, making change more feasible once they return to their hospitals.


Who should attend

IFAD 2026 is aimed at multidisciplinary clinicians involved in fluid therapy and the care of acutely ill or high-risk surgical patients. Intensivists, anesthesiologists, emergency physicians, internists, perioperative clinicians, and advanced practice nurses or physician assistants with an interest in critical care and perioperative medicine will all find the content directly relevant.

The structure of the meeting makes it accessible to participants with different levels of prior exposure to advanced hemodynamic concepts. Early-career clinicians can use the course to build a robust foundation, while experienced practitioners can refine their practice, update their knowledge, and benchmark their own approaches against international perspectives. The limited group size and emphasis on discussion create a setting where diverse disciplines can learn from each other and build shared language around fluid stewardship.


Practical details and next steps

IFAD 2026 – the 15th anniversary International Fluid Academy Days – will take place from 3–5 December 2026 in ZAS Cadix, Antwerp, Belgium. The meeting is offered as a three-day, course-based experience, with a structured program that progresses from foundational principles to advanced clinical application and an interactive quiz/diploma-style closing session.

Participation is intentionally limited to protect interaction and ensure the quality of the learning journey. A detailed program, including session formats and faculty list, will be released and updated over time on the official website. Information on registration, logistics, and any future updates will also be provided there as they become available.

Visit the official International Fluid Academy website to explore IFAD 2026:

Marvin Zick
Lieke’s Sepsis Story: From Unimaginable Loss to Life-Saving Awareness

On January 4, 2026, our lives changed forever.

Our daughter, Lieke, died from sepsis. She was only two years old.

Lieke was a cheerful, loving, and curious little girl. She loved dancing, cuddling, playing outside, and discovering the world around her. She found joy in the smallest things and had a smile that could light up any room. To us, she was our greatest happiness.

Like every parent, we believed that if our daughter ever became seriously ill, modern healthcare would be able to help her. 

We never imagined that we would lose her within just a few days.

On New Year's Eve, December 31, 2025, Lieke became ill. At first, it seemed like the flu or a common viral infection—something many young children experience during the winter months.

But something didn't feel right.

On January 1, we sought medical attention. We returned to the general practitioner again on January 2, and once more on January 3. Every day we saw that Lieke was not getting better. Every day, as parents, we felt that something was wrong. 

As a parent, you know your child.

You notice when their smile disappears.

You notice when they no longer behave like themselves.

And sometimes you simply can't explain it—you just know, deep down, that something is seriously wrong.

Unfortunately, the early symptoms of sepsis are often difficult to recognize. They closely resemble those of the flu or a common viral infection. That is exactly why sepsis is still diagnosed far too late, when every minute counts.

On January 4, we knew we had to seek help once again.

For the fourth time, we took Lieke to our general practitioner.

That was the moment everything changed.

Within minutes, it became clear how critically ill she was.

Less than two hours later, we had to say goodbye to our daughter.

She died from sepsis.

She was only two years old.

Less than a week earlier, we had celebrated Christmas together.

Less than five days earlier, we had welcomed the New Year as a family.

No parent ever expects life to change so completely in such a short period of time.

Until that day, we had never even heard of sepsis.

We didn't know how quickly it could become life-threatening.

We didn't know that every hour matters.

And we didn't know that sepsis affects millions of people worldwide every year and remains one of the leading causes of death across the globe.

Since losing Lieke, one question has stayed with us every single day. 

What if we had known about sepsis sooner?

We will never know the answer.

But we do know one thing.

If we had known what sepsis was before January 4, we would have done everything in our power to make sure other families had that knowledge. 

That is why we decided that Lieke's story could not end on the day she died.

On March 10, 2026, we founded the Voor Lieke Foundation.

Not because we had left our grief behind.

We never will.

But because we believed that Lieke's story could save lives.

Our mission is simple:

To make sure everyone knows what sepsis is.

Because recognizing sepsis saves lives.

Every day, we work to raise awareness among parents, healthcare professionals, schools, sports clubs, childcare organizations, businesses, and communities.

We provide education, develop awareness materials, organize campaigns, collaborate with healthcare organizations, and actively engage with the media.

Not because we want to keep telling our own story.

But because every family deserves to know the warning signs of sepsis before it is too late.

Our foundation was not created out of anger.

It was created out of love.

Love for our daughter.

 And from the belief that no family should have to experience the unimaginable pain of losing a child because sepsis was not recognized in time.

We cannot bring Lieke back.

But perhaps her story can help save another child.

Perhaps her story will give a parent the confidence to trust their instincts.

Perhaps her story will encourage a healthcare professional to consider sepsis just a little earlier.

And perhaps her story will mean that another child is still alive tomorrow.

That is why we continue.

For Lieke.

For every parent. 

For every child.

For greater awareness.

For earlier recognition. 

For more lives.

 

Because recognizing sepsis saves lives.


The article above was written by Meran Bosgraaf, Lieke’s father, and is shared here with his explicit consent. The views in the article do not necessarily represent those of the Global Sepsis Alliance. They are not intended or implied to be a substitute for professional medical advice. The whole team here at the Global Sepsis Alliance and World Sepsis Day wishes to thank Meran and his wife for sharing Lieke’s story and for fighting to raise awareness for sepsis.

Marvin Zick
New Date, 7 July: STAIRS Global Sepsis Lecture on Surviving Sepsis Campaign International Guidelines (SSC) in Children 2026

The STAIRS Consortium will host the next lecture of the STAIRS Global Sepsis Lecture Series on Tuesday, July 7 at 6pm EAT / 3pm GMT / 5pm CEST.  Dr. Eugene Martey, MD, Pediatric Critical Care Specialist at Komfo Anokye Teaching Hospital in Kumasi, Ghana, will present the second part of a two-part series about the updated Surviving Sepsis Campaign International Guidelines (SSC) in Children 2026.

We look forward to an engaging and highly insightful session with Dr. Martey, offering valuable updates for all participants working in pediatric critical care and beyond.

We warmly encourage you to join us and to share this invitation widely within your network.

Registration

If you have not yet registered, please do so via the button below or with the QR- code above.

Missed a Live Session?

 Last session on the 2026 SSC Updates on the Definition and Diagnosis of Pediatric Sepsis, as well as recordings of all past sessions, have been made available on Learning-STAIRS and YouTube. We encourage you to use these resources and to visit the STAIRS website for additional content and the latest publications on sepsis in low- and middle-income settings

About the Series

The STAIRS Global Sepsis Lecture Series brings together leading experts from Africa and beyond to support capacity strengthening and knowledge exchange on all aspects of sepsis. With a focus on both adult and pediatric care, the series highlights clinical management from an interprofessional perspective and explores topics such as infection prevention, antimicrobial resistance, telemedicine, and quality improvement

Lectures are held bi-weekly over 24 months and are open to clinicians, nurses, students, and healthcare professionals across STAIRS partner countries—and beyond. Please feel free to share this invitation widely within your networks.

CPD Points and E-Certificates

We are working with various institutions to offer CPD accreditation. Participants affiliated with the Arsi University CPD Center (Ethiopia) are already eligible for CPD points. To register for CPD points via Arsi University, please complete the following form: CPD Registration Form. E-certificates will be issued for the attended lectures.


For any questions, please contact us at stairs-sepsis@charite.de.

Simone Mancini
Watch the Recording: Antibiotic Stewardship for the Critically-Ill: New and Emerging Evidence

Update: The webinar is now available to rewatch above and on YouTube, including chapter markers, so you can jump right to the topic/speaker that interests you most.


Join us today for the second webinar in the European Sepsis Alliance’s series on Antibiotic Stewardship in the Critically-Ill.

This free webinar, featuring Prof. Matteo Bassetti and Dr. Luke Moore and moderated by ESA Chair Prof. Evangelos Giamarellos-Bourboulis, will prioritize new and emerging evidence, behavioral and organizational aspects of antibiotic stewardship, and gaps between evidence and real-world practice, with a discussion on how to improve adherence and optimize patient outcomes.

The event recording will be available at the same URL immediately after the livestream has concluded.


About This Webinar Series

The European Sepsis Alliance webinar series on antibiotic stewardship in critically-ill patients will bring together leading international experts to discuss the latest evidence, practical implementation strategies, and real-world clinical challenges in antimicrobial stewardship.

Across two live sessions on June 4 and June 17, participants will explore topics including biomarker-guided stewardship, bedside implementation, behavioral and human factors that influence protocol adherence, and emerging research that will shape future practice.

The webinars will feature expert presentations, case-based discussions, and interactive live Q&A sessions with internationally recognized specialists in intensive care, infectious diseases, and sepsis care.


Sponsored by Thermo Fisher Scientific

This webinar is kindly supported by Thermo Fisher Scientific, whom we sincerely thank for their continued support. Sponsors do not influence the choice of speakers or the content of the webinar in any way.

 
 
Marvin Zick